at 6 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T13561	AT6		Others
	AT6 is a PROTAC AT1 analog which is a highly selective bromodomain (Brd4) degrader.		Others
T2344	LY 344864	LY344864	5-HT Receptor
	LY 344864, a specifc receptor agonist, is an affinity of 6 nM (Ki) at the recently cloned 5-HT1F receptor.		5-HT Receptor
T3S1967	(S)-Indoximod	N-ME-Tryptophan,Abrine,L-Abrine	Others , Indoleamine 2,3-Dioxygenase (IDO)
	(S)-Indoximod (L-Abrine) exhibits inhibition of rabbit small intestine indoleamine 2, 3-dioxygenase, competitive inhibition of IDO, reduction of Foxp3 protein expression in tumor of C57BL/6 mouse allografted with mouse L...		Others , Indoleamine 2,3-Dioxygenase (IDO)
TN1325	(2S)-6-Prenylnaringenin	6-Prenylnaringenin,6-PN	GABA Receptor
	(2S)-6-Prenylnaringenin (6-Prenylnaringenin) is an isomer of the potent phytoestrogen, 8-prenylnaringenin. (2S)-6-Prenylnaringenin is the most potent compound in the forebrain and acts as a positive allosteric modulator ...		GABA Receptor
T3725	K-Ras(G12C) Inhibitor 6		Raf
	K-Ras(G12C) inhibitor 6 is an irreversible, allosteric inhibitor of the K-Ras(G12C) mutant that causes 100% modification of the protein when used at 10 μM for 24 hours in vitro.		Raf
T0717	Enoxacin hydrate	CI-919 hydrate,Enoxacin Sesquihydrate,AT-2266 hydrate	DNA gyrase , DNA/RNA Synthesis , Topoisomerase , Antibacterial , Antibiotic
	Enoxacin hydrate (AT-2266 hydrate) is a broad-spectrum 6-fluoronaphthyridinone antibacterial agent.
T16435	PBIT		Histone Demethylase , Histone Methyltransferase
	PBIT inhibits JARID1B histone demethylase (IC50 of about 3 μM). PBIT also inhibits JARID1A and JARID1C (IC50s of 6 μM and 4.9 μM, respectively). PBIT is a specific inhibitor of the Jumonji AT-rich Interactive Domain 1 (J...		Histone Demethylase , Histone Methyltransferase
T6598	MPEP		GluR
	MPEP is a selective mGlu5 receptor antagonist with IC50 of 36 nM, exhibits no appreciable activity at mGlu1b/2/3/4a/7b/8a/6 receptors.		GluR
T19262	D-Glucose 6-phosphate disodium salt	D-Glucose 6-phosphate disodium salt	Endogenous Metabolite
	D-Glucose 6-phosphate disodium salt is a compound widely present in biological systems. It is a molecule formed when glucose undergoes phosphorylation at the 6th carbon. This compound participates in various metabolic re...		Endogenous Metabolite
TD0101	AQC	6-Aminoquinolyl-N-hydroxysccinimidyl carbamate	Others
	AQC (6-Aminoquinolyl-N-hydroxysccinimidyl carbamate) (6-Aminoquinolyl-N-hydroxysccinimidyl carbamate) is a reagent for the fluorescence detection of amino acid or protein sequence by HPLC. AQC reacts with primary and sec...		Others
T10781	CGP 78608 hydrochloride	PAMQX	NMDAR , iGluR
	CGP 78608 hydrochloride is a specific antagonist at the glycine binding site of the NMDA receptor (IC50 = 6 nM). CGP 78608 hydrochloride exhibits anticonvulsant activity. CGP 78608 hydrochloride potentiates GluN1/GluN3A-...		NMDAR , iGluR
T4726	D-Glucose 6-phosphate sodium	G6P sodium salt,D-Glucose 6-phosphate sodium salt,Sodium Glucose-6-Phosphate	Others , Endogenous Metabolite
	In cells, D-Glucose 6-phosphate sodium (G6P) is generated when glucose is phosphorylated by hexokinase or glucokinase or by the conversion of glucose-1-phosphate by phosphoglucomutase during glycogenolysis. G6P lies at t...		Others , Endogenous Metabolite
T22735	DMAB-anabaseine dihydrochloride	N,N-dimethyl-4-[(E)-(6-pyridin-3-yl-3,4-dihydro-2H-pyridin-5-ylidene)methyl]aniline;dihydrochloride	AChR
	DMAB-anabaseine dihydrochloride (N,N-dimethyl-4-[(E)-(6-pyridin-3-yl-3,4-dihydro-2H-pyridin-5-ylidene)methyl]aniline;dihydrochloride) is an α7-containing neuronal nicotinic receptor partial agonist and an antagonist at α...		AChR
T10432L	AZD-8529 mesylate		GluR
	AZD-8529 mesylate is a highly selective, and orally bioavailable positive allosteric modulator of mGluR2 (EC50: 285 nM). It shows no positive allosteric modulator responses at 20-25 M on the mGluR1, 3, 4, 5, 6, 7, and 8 ...		GluR
T15728	LDN-212320	LDN-0212320,LDN/OSU-0212320,OSU-0212320	transporter
	LDN-212320 (OSU-0212320) is a glutamate transporter EAAT2 activator. It also enhances EAAT2 levels by > 6 fold at concentrations < 5 μM after 24 h.		transporter
T21532	Anisodamine	6-Hydroxyhyoscyamine,6-beta-Hydroxyhyoscyamine	AChR
	Anisodamine (6-beta-Hydroxyhyoscyamine) is an antagonist of muscarinic and nicotinic cholinoceptor with similar affinities at the muscarinic receptor as scopolamine and atropine. Anisodamine improve the microcirculation ...		AChR
T16962	SW-100		HDAC
	SW-100 is a selective histone deacetylase 6 inhibitor (IC50: 2.3 nM). It also shows at least 1000-fold selectivity for HDAC6 relative to all other HDAC isozymes. SW-100 displays an obviously improved ability to cross the...		HDAC
T12574	PTC299	Emvododstat,(4-chlorophenyl) (1S)-6-chloro-1-(4-methoxyphenyl)-1,3,4,9-tetrahydropyrido[3,4-b]indole-2-carboxylate	VEGFR , Dehydrogenase
	PTC299 ((4-chlorophenyl) (1S)-6-chloro-1-(4-methoxyphenyl)-1,3,4,9-tetrahydropyrido[3,4-b]indole-2-carboxylate) is an orally active inhibitor of VEGFA mRNA translation and selectively inhibits VEGF protein synthesis at t...		VEGFR , Dehydrogenase
T3794	Pentagalloylglucose	Penta-O-galloyl-β-D-glucose,1,2,3,4,6-O-Pentagalloylglucose,1,2,3,4,6-Penta-O-galloyl-beta-D-glucopyranose	Influenza Virus
	1, 2, 3, 4, 6-Pentagalloylglucose (Penta-O-galloyl-β-D-glucose) and gallic acid from Pistacia lentiscus have antimutagenic and antioxidant activities. 2. 1, 2, 3, 4, 6-Penta-O-galloyl-beta-D-glucose (PGG) possesses poten...		Influenza Virus
T3398	Icaritin	Anhydroicaritin,Cycloicaritin	Apoptosis , JAK , STAT , Autophagy
	Icaritin (Anhydroicaritin) has hormone regulation activity and cardiovascular function improvement activity. Icaritin has anticancer activity, can induce S phase arrest and apoptosis, inhibit ENKL cell proliferation. Ica...		Apoptosis , JAK , STAT , Autophagy